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Sulforaphane reduces YAP/∆Np63α signaling to reduce cancer stem cell survival and tumor formation
Epidermal squamous cell carcinoma (SCC) is among the most common cancers. SCC can be treated by surgical excision, but recurrence of therapy-resistant disease is a major problem. We recently showed that YAP1, the Hippo signaling transcription adaptor protein, and ∆Np63α, a key epidermal stem cell su...
Autores principales: | Fisher, Matthew L., Ciavattone, Nicholas, Grun, Daniel, Adhikary, Gautam, Eckert, Richard L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650271/ https://www.ncbi.nlm.nih.gov/pubmed/29088716 http://dx.doi.org/10.18632/oncotarget.20562 |
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