Enhanced immunotherapy by combining a vaccine with a novel murine GITR ligand fusion protein

Immunotherapy was significantly enhanced in a murine tumor model by combining a vaccine with a fusion protein designed to target the glucocorticoid-induced tumor necrosis factor (TNF) receptor related gene (GITR) on the surface of T cells. The recombinant poxvirus-based vaccine platform included Mod...

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Detalles Bibliográficos
Autores principales: Morillon, Y. Maurice, Hammond, Scott A., Durham, Nicholas M., Schlom, Jeffrey, Greiner, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650275/
https://www.ncbi.nlm.nih.gov/pubmed/29088720
http://dx.doi.org/10.18632/oncotarget.20703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650275/
https://www.ncbi.nlm.nih.gov/pubmed/29088720
http://dx.doi.org/10.18632/oncotarget.20703

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