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Enhanced immunotherapy by combining a vaccine with a novel murine GITR ligand fusion protein

Immunotherapy was significantly enhanced in a murine tumor model by combining a vaccine with a fusion protein designed to target the glucocorticoid-induced tumor necrosis factor (TNF) receptor related gene (GITR) on the surface of T cells. The recombinant poxvirus-based vaccine platform included Mod...

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Detalles Bibliográficos
Autores principales:	Morillon, Y. Maurice, Hammond, Scott A., Durham, Nicholas M., Schlom, Jeffrey, Greiner, John W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Priority Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650275/ https://www.ncbi.nlm.nih.gov/pubmed/29088720 http://dx.doi.org/10.18632/oncotarget.20703

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