Dysfunctional transcripts are formed by alternative polyadenylation in OPMD

Post-transcription mRNA processing in the 3’-untranslated region (UTR) of transcripts alters mRNA landscape. Alternative polyadenylation (APA) utilization in the 3’-UTR often leads to shorter 3’-UTR affecting mRNA stability, a process that is regulated by PABPN1. In skeletal muscles PABPN1 levels re...

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Detalles Bibliográficos
Autores principales: Raz, Vered, Dickson, George, ’t Hoen, Peter A.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650278/
https://www.ncbi.nlm.nih.gov/pubmed/29088723
http://dx.doi.org/10.18632/oncotarget.20640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650278/
https://www.ncbi.nlm.nih.gov/pubmed/29088723
http://dx.doi.org/10.18632/oncotarget.20640

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