Cargando…

Inflexibility of AMPK-mediated metabolic reprogramming in mitochondrial disease

Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is most commonly caused by the A3243G mutation of mitochondrial DNA. The capacity to utilize fatty acid or glucose as a fuel source and how such dynamic switches of metabolic fuel preferences and transcriptio...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Dar-Shong, Kao, Shu-Huei, Ho, Che-Sheng, Wei, Yau-Huei, Hung, Pi-Lien, Hsu, Mei-Hsin, Wu, Tsu-Yen, Wang, Tuan-Jen, Jian, Yuan-Ren, Lee, Tsung-Han, Chiang, Ming-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650287/
https://www.ncbi.nlm.nih.gov/pubmed/29088732
http://dx.doi.org/10.18632/oncotarget.20617