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Chondroitin sulfate proteoglycan serglycin influences protein cargo loading and functions of tumor-derived exosomes

Tumor cells produce and utilize exosomes to promote tumor growth and metastasis. Tumor-cell-derived exosomes deliver cargos that partially mimic the contents of the parent cell to nearby or distant normal or abnormal cells, thereby reprogramming the recipient cells to support tumor progression. Mech...

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Detalles Bibliográficos
Autores principales: Purushothaman, Anurag, Bandari, Shyam K., Chandrashekar, Darshan S., Jones, Richard J., Lee, Hans C., Weber, Donna M., Orlowski, Robert Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650294/
https://www.ncbi.nlm.nih.gov/pubmed/29088739
http://dx.doi.org/10.18632/oncotarget.20564