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Cystatin C deficiency suppresses tumor growth in a breast cancer model through decreased proliferation of tumor cells

Cysteine cathepsins are proteases that, in addition to their important physiological functions, have been associated with multiple pathologies, including cancer. Cystatin C (CstC) is a major endogenous inhibitor that regulates the extracellular activity of cysteine cathepsins. We investigated the ro...

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Detalles Bibliográficos
Autores principales: Završnik, Janja, Butinar, Miha, Prebanda, Mojca Trstenjak, Krajnc, Aleksander, Vidmar, Robert, Fonović, Marko, Grubb, Anders, Turk, Vito, Turk, Boris, Vasiljeva, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650301/
https://www.ncbi.nlm.nih.gov/pubmed/29088746
http://dx.doi.org/10.18632/oncotarget.17379