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CyclinD1 and p57(kip2) as biomarkers in differentiation, metastasis and prognosis of gastric cardia adenocarcinoma

OBJECTIVE: This study aims to investigate the expression and significance of p57(kip2) and cyclinD1 in gastric cardia adenocarcinoma (GCA). p57(kip2) is a negative regulator in the cell cycle. On the contrary, cyclinD1 is a positive regulator of cell cycle progression. METHODS: Thirty-two cases of G...

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Detalles Bibliográficos
Autores principales: Ru, Yi, Chen, Xiao-Jie, Zhao, Zhi-Wei, Zhang, Peng-Fei, Feng, Shuai-Hao, Gao, Qiang, Gao, She-Gan, Feng, Xiao-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650307/
https://www.ncbi.nlm.nih.gov/pubmed/29088752
http://dx.doi.org/10.18632/oncotarget.18008