Suppression of hypoxia-induced excessive angiogenesis by metformin via elevating tumor blood perfusion

The anti-diabetic metformin has been demonstrated to be effective in suppression of tumor progression via multiple mechanisms, in which angiogenic inhibition is involved. Hypoxia is a common feather of malignant tumor and promotes angiogenesis via induction of pro-angiogenic factors. However, the ef...

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Detalles Bibliográficos
Autores principales: Wang, Ji-Chang, Li, Guang-Yue, Li, Ping-Ping, Sun, Xin, Li, Wei-Ming, Li, Yan, Lu, Shao-Ying, Liu, Pei-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650310/
https://www.ncbi.nlm.nih.gov/pubmed/29088755
http://dx.doi.org/10.18632/oncotarget.18029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650310/
https://www.ncbi.nlm.nih.gov/pubmed/29088755
http://dx.doi.org/10.18632/oncotarget.18029

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