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trans-4,4’-Dihydroxystilbene (DHS) inhibits human neuroblastoma tumor growth and induces mitochondrial and lysosomal damages in neuroblastoma cell lines

In view of the inadequacy of neuroblastoma treatment, five hydroxystilbenes and resveratrol (Resv) were screened for their cytotoxic property against human neuroblastoma cell lines. The mechanism of cytotoxic action of the most potent compound, trans-4,4’-dihydroxystilbene (DHS) was investigated in...

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Detalles Bibliográficos
Autores principales: Saha, Bhaskar, Patro, Birija Sankar, Koli, Mrunesh, Pai, Ganesh, Ray, Jharna, Bandyopadhyay, Sandip K., Chattopadhyay, Subrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650311/
https://www.ncbi.nlm.nih.gov/pubmed/29088756
http://dx.doi.org/10.18632/oncotarget.17879