Combined inhibition of AKT and HSF1 suppresses breast cancer stem cells and tumor growth

Breast cancer is the most common cancer in women and the second leading cause of cancer deaths in women. Over 90% of breast cancer deaths are attributable to metastasis. Our lab has recently reported that AKT activates heat shock factor 1 (HSF1), leading to epithelial-to-mesenchymal transition in HE...

Descripción completa

Detalles Bibliográficos
Autores principales: Carpenter, Richard L., Sirkisoon, Sherona, Zhu, Dongqin, Rimkus, Tadas, Harrison, Alexandria, Anderson, Ashley, Paw, Ivy, Qasem, Shadi, Xing, Fei, Liu, Yin, Chan, Michael, Metheny-Barlow, Linda, Pasche, Boris C., Debinski, Waldemar, Watabe, Kounosuke, Lo, Hui-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650314/
https://www.ncbi.nlm.nih.gov/pubmed/29088759
http://dx.doi.org/10.18632/oncotarget.18166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650314/
https://www.ncbi.nlm.nih.gov/pubmed/29088759
http://dx.doi.org/10.18632/oncotarget.18166

Ejemplares similares