BRCA1 and BRCA2 founder mutations account for 78% of germline carriers among hereditary breast cancer families in Chile

Identifying founder mutations in BRCA1 and BRCA2 in specific populations constitute a valuable opportunity for genetic screening. Several studies from different populations have reported recurrent and/or founder mutations representing a relevant proportion of BRCA mutation carriers. In Latin America...

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Detalles Bibliográficos
Autores principales: Alvarez, Carolina, Tapia, Teresa, Perez-Moreno, Elisa, Gajardo-Meneses, Patricia, Ruiz, Catalina, Rios, Mabel, Missarelli, Claudio, Silva, Mariela, Cruz, Adolfo, Matamala, Luis, Carvajal-Carmona, Luis, Camus, Mauricio, Carvallo, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650336/
https://www.ncbi.nlm.nih.gov/pubmed/29088781
http://dx.doi.org/10.18632/oncotarget.18815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650336/
https://www.ncbi.nlm.nih.gov/pubmed/29088781
http://dx.doi.org/10.18632/oncotarget.18815

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