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Melatonin attenuated the brain damage and cognitive impairment partially through MT2 melatonin receptor in mice with chronic cerebral hypoperfusion
BACKGROUND: Vascular cognitive impairment (VCI) is a spectrum of cognitive impairment caused by various chronic diseases including aging, hypertension, and diabetes mellitus. Oxidative and inflammatory reactions induced by chronic cerebral hypoperfusion (CHP) are believed to cause VCI. Melatonin is...
Autores principales: | Tsai, Tzu-Hsien, Lin, Cheng-Jei, Chua, Sarah, Chung, Sheng-Ying, Yang, Cheng-Hsu, Tong, Meng-Shen, Hang, Chi-Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650343/ https://www.ncbi.nlm.nih.gov/pubmed/29088788 http://dx.doi.org/10.18632/oncotarget.20382 |
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