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Fatty acid synthase expression and its association with clinico-histopathological features in triple-negative breast cancer

Triple-Negative Breast Cancer (TNBC) has poor prognosis and no approved targeted therapy. We previously showed that the enzyme fatty acid synthase (FASN) was largely expressed in a small TNBC patients’ cohort and its inhibition synergized with cetuximab in TNBC preclinical mouse models. Here, we eva...

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Detalles Bibliográficos
Autores principales: Giró-Perafita, Ariadna, Sarrats, Ariadna, Pérez-Bueno, Ferran, Oliveras, Glòria, Buxó, Maria, Brunet, Joan, Viñas, Gemma, Miquel, Teresa Puig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650350/
https://www.ncbi.nlm.nih.gov/pubmed/29088795
http://dx.doi.org/10.18632/oncotarget.20152