Lysine-specific demethylase 1 (LSD1) destabilizes p62 and inhibits autophagy in gynecologic malignancies

Lysine-specific demethylase 1 (LSD1) – also known as KDM1A – is the first identified histone demethylase. LSD1 is highly expressed in numerous human malignancies and has recently emerged as a target for anticancer drugs. Owing to the presence of several functional domains, we speculated that LSD1 co...

Descripción completa

Detalles Bibliográficos
Autores principales: Chao, Angel, Lin, Chiao-Yun, Chao, An-Ning, Tsai, Chia-Lung, Chen, Ming-Yu, Lee, Li-Yu, Chang, Ting-Chang, Wang, Tzu-Hao, Lai, Chyong-Huey, Wang, Hsin-Shih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650353/
https://www.ncbi.nlm.nih.gov/pubmed/29088798
http://dx.doi.org/10.18632/oncotarget.20158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650353/
https://www.ncbi.nlm.nih.gov/pubmed/29088798
http://dx.doi.org/10.18632/oncotarget.20158

Ejemplares similares