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Lysine-specific demethylase 1 (LSD1) destabilizes p62 and inhibits autophagy in gynecologic malignancies
Lysine-specific demethylase 1 (LSD1) – also known as KDM1A – is the first identified histone demethylase. LSD1 is highly expressed in numerous human malignancies and has recently emerged as a target for anticancer drugs. Owing to the presence of several functional domains, we speculated that LSD1 co...
Autores principales: | Chao, Angel, Lin, Chiao-Yun, Chao, An-Ning, Tsai, Chia-Lung, Chen, Ming-Yu, Lee, Li-Yu, Chang, Ting-Chang, Wang, Tzu-Hao, Lai, Chyong-Huey, Wang, Hsin-Shih |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650353/ https://www.ncbi.nlm.nih.gov/pubmed/29088798 http://dx.doi.org/10.18632/oncotarget.20158 |
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