Maslinic acid promotes autophagy by disrupting the interaction between Bcl2 and Beclin1 in rat pheochromocytoma PC12 cells

Maslinic acid (2α, 3β-dihydroxyolean-12-en-28-oic acid, MA) was isolated from natural plants and showed anti-cancer activity in rat Pheochromocytoma PC12 cells in our previous studies. We now discover that MA disrupts the interaction between Bcl2 and autophagy scaffold protein Beclin1 in the above c...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Xiaoli, Zhang, Jiaxiao, Zhou, Zhilin, Ye, Zhennan, Chen, Jiahao, Yuan, Jifan, Cao, Fengjun, Wang, Xuanbin, Liu, Wenchao, Yu, Wenxuan, Li, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650360/
https://www.ncbi.nlm.nih.gov/pubmed/29088805
http://dx.doi.org/10.18632/oncotarget.20210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650360/
https://www.ncbi.nlm.nih.gov/pubmed/29088805
http://dx.doi.org/10.18632/oncotarget.20210

Ejemplares similares