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Downregulation of microRNA-31 inhibits proliferation and induces apoptosis by targeting HIF1AN in human keloid

microRNAs (miRNAs) play a pivotal role in the regulation of cell proliferation and apoptosis in keloid scarring. Integrative analysis of the previous miRNA microarray revealed miRNA-31 was among the most frequently altered miRNAs in keloid and hypertrophic scar. Using qRT-PCR, we further validated m...

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Detalles Bibliográficos
Autores principales: Zhang, Juan, Xu, Dan, Li, Na, Li, Yan, He, Yongjing, Hu, Xingbo, Lyu, Lechun, He, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650367/
https://www.ncbi.nlm.nih.gov/pubmed/29088812
http://dx.doi.org/10.18632/oncotarget.20284