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Radiation-resistant cancer stem-like cell properties are regulated by PTEN through the activity of nuclear β-catenin in nasopharyngeal carcinoma

Radiotherapy is the primary and most important treatment for nasopharyngeal carcinoma (NPC). Cancer stem-like cells (CSCs) have been shown to be resistant to radiation. The phosphatase and tensin homolog deleted on chromosome 10 (PTEN) tumor suppressor gene has been suggested to play a role in stem...

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Detalles Bibliográficos
Autores principales: Zhang, Gong, Wang, Wenjun, Yao, Chunxiao, Zhang, Shuping, Liang, Lili, Han, Muyuan, Ren, Jinjin, Qi, Xiurong, Zhang, Xiaofeng, Wang, Shuye, Li, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650370/
https://www.ncbi.nlm.nih.gov/pubmed/29088815
http://dx.doi.org/10.18632/oncotarget.20339