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Cigarette smoke promotes COPD by activating platelet-activating factor receptor and inducing neutrophil autophagic death in mice

Neutrophils are the most important effector cells during the development of chronic obstructive pulmonary disease (COPD). Although neutrophil elastase is critical in cigarette smoke (CS)-induced lung parenchyma, the mechanism by which CS triggers elastase release from neutrophils remains unclear. He...

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Detalles Bibliográficos
Autores principales: Lv, Xiao-Xi, Liu, Shan-Shan, Li, Ke, Cui, Bing, Liu, Chang, Hu, Zhuo-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650374/
https://www.ncbi.nlm.nih.gov/pubmed/29088819
http://dx.doi.org/10.18632/oncotarget.20353