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Diallyl trisulfide exerts cardioprotection against myocardial ischemia-reperfusion injury in diabetic state, role of AMPK-mediated AKT/GSK-3β/HIF-1α activation

Diallyl trisulfide (DATS), the major active ingredient in garlic, has been reported to confer cardioprotective effects. However, its effect on myocardial ischemia-reperfusion (MI/R) injury in diabetic state and the underlying mechanism are still unknown. We hypothesize that DATS reduces MI/R injury...

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Detalles Bibliográficos
Autores principales: Yu, Liming, Di, Wencheng, Dong, Xue, Li, Zhi, Xue, Xiaodong, Zhang, Jian, Wang, Qi, Xiao, Xiong, Han, Jinsong, Yang, Yang, Wang, Huishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650379/
https://www.ncbi.nlm.nih.gov/pubmed/29088824
http://dx.doi.org/10.18632/oncotarget.20422