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Let-7d increases ovarian cancer cell sensitivity to a genistein analog by targeting c-Myc

c-Myc is a key oncogenic transcription factor that participates in tumor pathogenesis. In this study, we found that levels of c-Myc mRNA and protein were higher in early ovarian cancer tissues than normal ovary samples. Increased c-Myc levels correlated positively with clinical stage I (Ia+b/Ic) in...

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Detalles Bibliográficos
Autores principales: Ning, Ying-Xia, Luo, Xin, Xu, Meng, Feng, Xin, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650382/
https://www.ncbi.nlm.nih.gov/pubmed/29088827
http://dx.doi.org/10.18632/oncotarget.20413