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Common, germline genetic variations in the novel tumor suppressor BAP1 and risk of developing different types of cancer

BRCA1 associated protein-1 (BAP1) is a novel tumor suppressor that has recently been shown to be somatically mutated in several cancers. The BAP1 gene also carries rare germline mutations in families with a high incidence of several types of cancers, such as mesothelioma, uveal melanoma, lung adenoc...

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Detalles Bibliográficos
Autores principales: Lin, Moubin, Zhang, Liren, Hildebrandt, Michelle A.T., Huang, Maosheng, Wu, Xifeng, Ye, Yuanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650391/
https://www.ncbi.nlm.nih.gov/pubmed/29088836
http://dx.doi.org/10.18632/oncotarget.20465