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Common, germline genetic variations in the novel tumor suppressor BAP1 and risk of developing different types of cancer
BRCA1 associated protein-1 (BAP1) is a novel tumor suppressor that has recently been shown to be somatically mutated in several cancers. The BAP1 gene also carries rare germline mutations in families with a high incidence of several types of cancers, such as mesothelioma, uveal melanoma, lung adenoc...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650391/ https://www.ncbi.nlm.nih.gov/pubmed/29088836 http://dx.doi.org/10.18632/oncotarget.20465 |