Cargando…

Metformin partially reverses the carboplatin-resistance in NSCLC by inhibiting glucose metabolism

Platinum-based chemotherapeutic drugs are irreplaceable for the treatment of advanced non-small cell lung cancer (NSCLC). However, acquired drug resistance has become a major obstacle for the clinical application of chemotherapy on NSCLC. In the present study, we established carboplatin-resistant NS...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yong, He, Chunxi, Huang, Xianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650413/
https://www.ncbi.nlm.nih.gov/pubmed/29088858
http://dx.doi.org/10.18632/oncotarget.20663