Novel histone deacetylase inhibitor N25 exerts anti-tumor effects and induces autophagy in human glioma cells by inhibiting HDAC3

N25, a novel histone deacetylase inhibitor, was created through structural modification of suberoylanilide hydroxamic acid. To evaluate the anti-tumor activity of N25 and clarify its molecular mechanism of inducing autophagy in glioma cells, we investigated its in vitro anti-proliferative effect and...

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Detalles Bibliográficos
Autores principales: Sun, Xin-Yuan, Qu, Yue, Ni, An-Ran, Wang, Gui-Xiang, Huang, Wei-Bin, Chen, Zhong-Ping, Lv, Zhu-Fen, Zhang, Song, Lindsay, Holly, Zhao, Sibo, Li, Xiao-Nan, Feng, Bing-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650415/
https://www.ncbi.nlm.nih.gov/pubmed/29088860
http://dx.doi.org/10.18632/oncotarget.20744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650415/
https://www.ncbi.nlm.nih.gov/pubmed/29088860
http://dx.doi.org/10.18632/oncotarget.20744

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