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Novel histone deacetylase inhibitor N25 exerts anti-tumor effects and induces autophagy in human glioma cells by inhibiting HDAC3

N25, a novel histone deacetylase inhibitor, was created through structural modification of suberoylanilide hydroxamic acid. To evaluate the anti-tumor activity of N25 and clarify its molecular mechanism of inducing autophagy in glioma cells, we investigated its in vitro anti-proliferative effect and...

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Detalles Bibliográficos
Autores principales:	Sun, Xin-Yuan, Qu, Yue, Ni, An-Ran, Wang, Gui-Xiang, Huang, Wei-Bin, Chen, Zhong-Ping, Lv, Zhu-Fen, Zhang, Song, Lindsay, Holly, Zhao, Sibo, Li, Xiao-Nan, Feng, Bing-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650415/ https://www.ncbi.nlm.nih.gov/pubmed/29088860 http://dx.doi.org/10.18632/oncotarget.20744

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