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1,25-Dihydroxyvitamin D Inhibits LPS-Induced High-Mobility Group Box 1 (HMGB1) Secretion via Targeting the NF-E2-Related Factor 2–Hemeoxygenase-1–HMGB1 Pathway in Macrophages
1,25-Dihydroxyvitamin D [1,25(OH)(2)D(3)] is recognized as a key mediator of inflammatory diseases, including sepsis. Clinical studies demonstrate that 1,25 (OH)(2)D(3) protects patients from sepsis, but clinical treatment with 1,25(OH)(2)D(3) is rare. In this study, we report that 1,25(OH)(2)D(3) t...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650703/ https://www.ncbi.nlm.nih.gov/pubmed/29085368 http://dx.doi.org/10.3389/fimmu.2017.01308 |