1,25-Dihydroxyvitamin D Inhibits LPS-Induced High-Mobility Group Box 1 (HMGB1) Secretion via Targeting the NF-E2-Related Factor 2–Hemeoxygenase-1–HMGB1 Pathway in Macrophages

1,25-Dihydroxyvitamin D [1,25(OH)(2)D(3)] is recognized as a key mediator of inflammatory diseases, including sepsis. Clinical studies demonstrate that 1,25 (OH)(2)D(3) protects patients from sepsis, but clinical treatment with 1,25(OH)(2)D(3) is rare. In this study, we report that 1,25(OH)(2)D(3) t...

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Detalles Bibliográficos
Autores principales: Rao, Zebing, Zhang, Na, Xu, Ning, Pan, Ying, Xiao, Mengjun, Wu, Junxian, Zhou, Hong, Yang, Shuo, Chen, Yunzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650703/
https://www.ncbi.nlm.nih.gov/pubmed/29085368
http://dx.doi.org/10.3389/fimmu.2017.01308

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