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HSP90 Inhibition and Cellular Stress Elicits Phenotypic Plasticity in Hematopoietic Differentiation

Cancer cells exist in a state of Darwinian selection using mechanisms that produce changes in gene expression through genetic and epigenetic alteration to facilitate their survival. Cellular plasticity, or the ability to alter cellular phenotype, can assist in survival of premalignant cells as they...

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Detalles Bibliográficos
Autores principales: Lawag, Abdalla A., Napper, Jennifer M., Hunter, Caroline A., Bacon, Nickolas A., Deskins, Seth, El-hamdani, Manaf, Govender, Sarah-Leigh, Koc, Emine C., Sollars, Vincent E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650721/
https://www.ncbi.nlm.nih.gov/pubmed/28910138
http://dx.doi.org/10.1089/cell.2017.0001