Cargando…
Presenilin 2-Dependent Maintenance of Mitochondrial Oxidative Capacity and Morphology
Mitochondrial dysfunction plays a pivotal role in the progression of Alzheimer's disease (AD), and yet the mechanisms underlying the impairment of mitochondrial function in AD remain elusive. Recent evidence suggested a role for Presenilins (PS1 or PS2) in mitochondrial function. Mutations of P...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650731/ https://www.ncbi.nlm.nih.gov/pubmed/29085303 http://dx.doi.org/10.3389/fphys.2017.00796 |