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Presenilin 2-Dependent Maintenance of Mitochondrial Oxidative Capacity and Morphology

Mitochondrial dysfunction plays a pivotal role in the progression of Alzheimer's disease (AD), and yet the mechanisms underlying the impairment of mitochondrial function in AD remain elusive. Recent evidence suggested a role for Presenilins (PS1 or PS2) in mitochondrial function. Mutations of P...

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Detalles Bibliográficos
Autores principales:	Contino, Sabrina, Porporato, Paolo E., Bird, Matthew, Marinangeli, Claudia, Opsomer, Rémi, Sonveaux, Pierre, Bontemps, Françoise, Dewachter, Ilse, Octave, Jean-Noël, Bertrand, Luc, Stanga, Serena, Kienlen-Campard, Pascal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650731/ https://www.ncbi.nlm.nih.gov/pubmed/29085303 http://dx.doi.org/10.3389/fphys.2017.00796

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