An Alignment-Independent 3D-QSAR Study of FGFR2 Tyrosine Kinase Inhibitors

Purpose: Receptor tyrosine kinase (RTK) inhibitors are widely used pharmaceuticals in cancer therapy. Fibroblast growth factor receptors (FGFRs) are members of RTK superfamily which are highly expressed on the surface of carcinoma associate fibroblasts (CAFs). The involvement of FGFRs in different t...

Descripción completa

Detalles Bibliográficos
Autores principales: Jafari, Behzad, Hamzeh-Mivehroud, Maryam, Alizadeh, Ali Akbar, Sharifi, Mehdi, Dastmalchi, Siavoush
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651062/
https://www.ncbi.nlm.nih.gov/pubmed/29071223
http://dx.doi.org/10.15171/apb.2017.049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651062/
https://www.ncbi.nlm.nih.gov/pubmed/29071223
http://dx.doi.org/10.15171/apb.2017.049

Ejemplares similares