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An Alignment-Independent 3D-QSAR Study of FGFR2 Tyrosine Kinase Inhibitors
Purpose: Receptor tyrosine kinase (RTK) inhibitors are widely used pharmaceuticals in cancer therapy. Fibroblast growth factor receptors (FGFRs) are members of RTK superfamily which are highly expressed on the surface of carcinoma associate fibroblasts (CAFs). The involvement of FGFRs in different t...
Autores principales: | Jafari, Behzad, Hamzeh-Mivehroud, Maryam, Alizadeh, Ali Akbar, Sharifi, Mehdi, Dastmalchi, Siavoush |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tabriz University of Medical Sciences
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651062/ https://www.ncbi.nlm.nih.gov/pubmed/29071223 http://dx.doi.org/10.15171/apb.2017.049 |
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