The Leukemic Stem Cell Niche: Adaptation to “Hypoxia” versus Oncogene Addiction

Previous studies based on low oxygen concentrations in the incubation atmosphere revealed that metabolic factors govern the maintenance of normal hematopoietic or leukemic stem cells (HSC and LSC). The physiological oxygen concentration in tissues ranges between 0.1 and 5.0%. Stem cell niches (SCN)...

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Detalles Bibliográficos
Autores principales: Cheloni, Giulia, Poteti, Martina, Bono, Silvia, Masala, Erico, Mazure, Nathalie M., Rovida, Elisabetta, Lulli, Matteo, Dello Sbarba, Persio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651121/
https://www.ncbi.nlm.nih.gov/pubmed/29118813
http://dx.doi.org/10.1155/2017/4979474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651121/
https://www.ncbi.nlm.nih.gov/pubmed/29118813
http://dx.doi.org/10.1155/2017/4979474

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