The neuroprotective effect of nicotine in Parkinson’s disease models is associated with inhibiting PARP-1 and caspase-3 cleavage

Clinical evidence points to neuroprotective effects of smoking in Parkinson’s disease (PD), but the molecular mechanisms remain unclear. We investigated the pharmacological pathways involved in these neuroprotective effects, which could provide novel ideas for developing targeted neuroprotective tre...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Justin Y.D., Su, Ping, Barber, James E.M., Nash, Joanne E., Le, Anh D., Liu, Fang, Wong, Albert H.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651169/
https://www.ncbi.nlm.nih.gov/pubmed/29062606
http://dx.doi.org/10.7717/peerj.3933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651169/
https://www.ncbi.nlm.nih.gov/pubmed/29062606
http://dx.doi.org/10.7717/peerj.3933

Ejemplares similares