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Molecular dynamics simulation analysis of Focal Adhesive Kinase (FAK) docked with solanesol as an anti-cancer agent

Focal adhesion kinase (FAK) plays a primary role in regulating the activity of many signaling molecules. Increased FAK expression has been associated in a series of cellular processes like cell migration and survival. FAK inhibition by an anti cancer agent is critical. Therefore, it is of interest t...

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Detalles Bibliográficos
Autores principales: Daneial, Betty, Joseph, Jacob Paul Vazhappilly, Ramakrishna, Guruprasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651220/
https://www.ncbi.nlm.nih.gov/pubmed/29081606
http://dx.doi.org/10.6026/97320630013274