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Use of a neural network to predict normalized signal strengths from a DNA-sequencing microarray

A microarray DNA sequencing experiment for a molecule of N bases produces a 4xN data matrix, where for each of the N positions each quartet comprises the signal strength of binding of an experimental DNA to a reference oligonucleotide affixed to the microarray, for the four possible bases (A, C, G,...

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Detalles Bibliográficos
Autores principales: Chilaka, Charles, Carr, Steven, Shalaby, Nabil, Banzhaf, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651225/
https://www.ncbi.nlm.nih.gov/pubmed/29081611
http://dx.doi.org/10.6026/97320630013313