RANTES/CCL5 Induces Collagen Degradation by Activating MMP-1 and MMP-13 Expression in Human Rheumatoid Arthritis Synovial Fibroblasts

Regulated on activation, normal T expressed, and secreted (RANTES)/CC ligand 5 (CCL5) participates in rheumatoid arthritis (RA) pathogenesis by facilitating leukocyte infiltration, however, its other pathological functions are not fully defined in RA. In the present study, we evaluated the effect of...

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Detalles Bibliográficos
Autores principales: Agere, Solomon A., Akhtar, Nahid, Watson, Jeffery M., Ahmed, Salahuddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651228/
https://www.ncbi.nlm.nih.gov/pubmed/29093715
http://dx.doi.org/10.3389/fimmu.2017.01341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651228/
https://www.ncbi.nlm.nih.gov/pubmed/29093715
http://dx.doi.org/10.3389/fimmu.2017.01341

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