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Dynamics of Heat Shock Protein 70 Serum Levels As a Predictor of Clinical Response in Non-Small-Cell Lung Cancer and Correlation with the Hypoxia-Related Marker Osteopontin

Hypoxia mediates resistance to radio(chemo)therapy (RT) by stimulating the synthesis of hypoxia-related genes, such as osteopontin (OPN) and stress proteins, including the major stress-inducible heat shock protein 70 (Hsp70). Apart from its intracellular localization, Hsp70 is also present on the pl...

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Detalles Bibliográficos
Autores principales: Ostheimer, Christian, Gunther, Sophie, Bache, Matthias, Vordermark, Dirk, Multhoff, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651249/
https://www.ncbi.nlm.nih.gov/pubmed/29093708
http://dx.doi.org/10.3389/fimmu.2017.01305