Isogenic Cellular Systems Model the Impact of Genetic Risk Variants in the Pathogenesis of Type 1 Diabetes

At least 57 independent loci within the human genome confer varying degrees of risk for the development of type 1 diabetes (T1D). The majority of these variants are thought to contribute to overall genetic risk by modulating host innate and adaptive immune responses, ultimately resulting in a loss o...

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Detalles Bibliográficos
Autores principales: Wallet, Mark A., Santostefano, Katherine E., Terada, Naohiro, Brusko, Todd M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651267/
https://www.ncbi.nlm.nih.gov/pubmed/29093700
http://dx.doi.org/10.3389/fendo.2017.00276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651267/
https://www.ncbi.nlm.nih.gov/pubmed/29093700
http://dx.doi.org/10.3389/fendo.2017.00276

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