Cyclic AC253, a novel amylin receptor antagonist, improves cognitive deficits in a mouse model of Alzheimer's disease

INTRODUCTION: Amylin receptor serves as a portal for the expression of deleterious effects of amyloid β-protein (Aβ), a key pathologic hallmark of Alzheimer's disease. Previously, we showed that AC253, an amylin receptor antagonist, is neuroprotective against Aβ toxicity in vitro and abrogates...

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Detalles Bibliográficos
Autores principales: Soudy, Rania, Patel, Aarti, Fu, Wen, Kaur, Kamaljit, MacTavish, David, Westaway, David, Davey, Rachel, Zajac, Jeffrey, Jhamandas, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651374/
https://www.ncbi.nlm.nih.gov/pubmed/29067318
http://dx.doi.org/10.1016/j.trci.2016.11.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651374/
https://www.ncbi.nlm.nih.gov/pubmed/29067318
http://dx.doi.org/10.1016/j.trci.2016.11.005

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