Targeting butyrylcholinesterase for preclinical single photon emission computed tomography (SPECT) imaging of Alzheimer's disease

INTRODUCTION: Diagnosis of Alzheimer's disease (AD) in vivo, by molecular imaging of amyloid or tau, is constrained because similar changes can be found in brains of cognitively normal individuals. Butyrylcholinesterase (BChE), which becomes associated with these structures in AD, could elevate...

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Detalles Bibliográficos
Autores principales: DeBay, Drew R., Reid, George A., Pottie, Ian R., Martin, Earl, Bowen, Chris V., Darvesh, Sultan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651425/
https://www.ncbi.nlm.nih.gov/pubmed/29067326
http://dx.doi.org/10.1016/j.trci.2017.01.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651425/
https://www.ncbi.nlm.nih.gov/pubmed/29067326
http://dx.doi.org/10.1016/j.trci.2017.01.005

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