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The effects of noncoding aquaporin-4 single-nucleotide polymorphisms on cognition and functional progression of Alzheimer's disease

INTRODUCTION: The glymphatic system is a brain-wide perivascular network that facilitates clearance of proteins, including amyloid β, from the brain interstitium through the perivascular exchange of cerebrospinal fluid and interstitial fluid. The astrocytic water channel aquaporin-4 (AQP4) is requir...

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Detalles Bibliográficos
Autores principales: Burfeind, Kevin G., Murchison, Charles F., Westaway, Shawn K., Simon, Matthew J., Erten-Lyons, Deniz, Kaye, Jeffrey A., Quinn, Joseph F., Iliff, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651426/
https://www.ncbi.nlm.nih.gov/pubmed/29067342
http://dx.doi.org/10.1016/j.trci.2017.05.001