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The effects of noncoding aquaporin-4 single-nucleotide polymorphisms on cognition and functional progression of Alzheimer's disease
INTRODUCTION: The glymphatic system is a brain-wide perivascular network that facilitates clearance of proteins, including amyloid β, from the brain interstitium through the perivascular exchange of cerebrospinal fluid and interstitial fluid. The astrocytic water channel aquaporin-4 (AQP4) is requir...
Autores principales: | Burfeind, Kevin G., Murchison, Charles F., Westaway, Shawn K., Simon, Matthew J., Erten-Lyons, Deniz, Kaye, Jeffrey A., Quinn, Joseph F., Iliff, Jeffrey J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651426/ https://www.ncbi.nlm.nih.gov/pubmed/29067342 http://dx.doi.org/10.1016/j.trci.2017.05.001 |
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