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Midlife anticholinergic drug use, risk of Alzheimer's disease, and brain atrophy in community-dwelling older adults
INTRODUCTION: We examined how long-term anticholinergic (AC) drug use beginning at midlife affects risk of Alzheimer's disease (AD) and rates of brain atrophy in cognitively normal older adults. METHODS: We followed 723 individuals (mean baseline age 52.3 years; mean follow-up interval 20.1 yea...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651434/ https://www.ncbi.nlm.nih.gov/pubmed/29067353 http://dx.doi.org/10.1016/j.trci.2017.06.004 |