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Midlife anticholinergic drug use, risk of Alzheimer's disease, and brain atrophy in community-dwelling older adults

INTRODUCTION: We examined how long-term anticholinergic (AC) drug use beginning at midlife affects risk of Alzheimer's disease (AD) and rates of brain atrophy in cognitively normal older adults. METHODS: We followed 723 individuals (mean baseline age 52.3 years; mean follow-up interval 20.1 yea...

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Detalles Bibliográficos
Autores principales:	Chuang, Yi-Fang, Elango, Palchamy, Gonzalez, Christopher E., Thambisetty, Madhav
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Featured Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651434/ https://www.ncbi.nlm.nih.gov/pubmed/29067353 http://dx.doi.org/10.1016/j.trci.2017.06.004

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