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Anthrax immune globulin improves hemodynamics and survival during B. anthracis toxin-induced shock in canines receiving titrated fluid and vasopressor support

BACKGROUND: Although anthrax immune globulin (AIG) improved survival in antibiotic-treated Bacillus anthracis-challenged animal models, whether it adds to the benefit of conventional hemodynamic support for B. anthracis toxin-associated shock is unknown. METHODS: We therefore tested AIG in sedated,...

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Detalles Bibliográficos
Autores principales: Suffredini, Dante A., Cui, Xizhong, Jaswal, Dharmvir, Remy, Kenneth E., Li, Yan, Sun, Junfeng, Solomon, Steven B., Fitz, Yvonne, Moayeri, Mahtab, Leppla, Stephen, Eichacker, Peter Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651533/
https://www.ncbi.nlm.nih.gov/pubmed/29058092
http://dx.doi.org/10.1186/s40635-017-0159-9