Evidence of reduced recombination rate in human regulatory domains

BACKGROUND: Recombination rate is non-uniformly distributed across the human genome. The variation of recombination rate at both fine and large scales cannot be fully explained by DNA sequences alone. Epigenetic factors, particularly DNA methylation, have recently been proposed to influence the vari...

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Detalles Bibliográficos
Autores principales: Liu, Yaping, Sarkar, Abhishek, Kheradpour, Pouya, Ernst, Jason, Kellis, Manolis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651596/
https://www.ncbi.nlm.nih.gov/pubmed/29058599
http://dx.doi.org/10.1186/s13059-017-1308-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651596/
https://www.ncbi.nlm.nih.gov/pubmed/29058599
http://dx.doi.org/10.1186/s13059-017-1308-x

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