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HIV-1 sequences in the epidemic suggest an alternative pathway for the generation of the Long Terminal Repeats

To generate the long-terminal repeats (LTR) that border the integrated viral genome, two-strand transfer steps must occur during reverse transcription. Analysis of the genetic polymorphisms that are present in the LTR of HIV-1 heterozygous virions in single infection cycle studies has revealed which...

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Detalles Bibliográficos
Autores principales: Cappy, Pierre, Moisan, Alice, De Oliveira, Fabienne, Plantier, Jean-Christophe, Negroni, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651808/
https://www.ncbi.nlm.nih.gov/pubmed/29057964
http://dx.doi.org/10.1038/s41598-017-14135-z